Is it possible to use custom bootloader to update firmware of BlueNRG-2 chip over SPI or I2C peripheral?

[KSoni.1]

I have a custom board with multiple MCUs and a BlueNRG-2 chip. I have a binary file of BlueNRG-2 in an external flash connected over SPI or I2C. 

I need to replace the existing application binary with the one stored in the external flash.

[Winfred LU]

It is possible.

You may want to reference BLE_OTA_ServiceManager project for customizing your own bootloader to use SPI or I2C flash accordingly.